Anti-HRSV Post-Fusion Glycoprotein Reference Antibody (ADI-14359, RUO) (VK421116)

价格:

规格：

100ug
1mg
5mg
10mg
25mg
50mg
100mg

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

货号	VK421116
品牌	abinScience
种属反应性	Human respiratory syncytial virus A (HRSV-A)
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG1, kappa
克隆号	ADI-14359
生物活性	ADI-14359 binds to epitope I of RSV postF via convergent CDR H3 motifs and germline-encoded features of its IGKV1-39 light chain and IGHV2-70 heavy chain, with key interactions mediated by specific hydrogen bonds and electrostatic contacts [1]. ADI-14359 (6.25 nM-1600 nM) binds to RSV postF with a K D value of 387 nM; the heavy chain Arg50 residue and postF Lys390 residue are critical for this interaction, as disruption of these residues significantly reduces or even completely abolishes binding [1]. ADI-14359 recognizes antigenic epitope I on RSV F, preferentially binds to the post-fusion conformation, and does not neutralize RSV [1].
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	F, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P03420
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	ADI-14359
背景	Fusion glycoprotein F0 is a ~63 kDa protein. Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins.
文献	1. Goodwin E, et al. Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity. 2018;48(2):339-349.e5. [VK421116]
Note	For research use only. Not suitable for clinical or therapeutic use.

SDS-PAGE

SDS-PAGE for Research Grade Anti-RSV F/Fusion glycoprotein F0 (ADI-14359)

产品说明书

Anti-HRSV Post-Fusion Glycoprotein Reference Antibody (ADI-14359, RUO).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-HRSV Post-Fusion Glycoprotein Reference Antibody (ADI-14359, RUO) (VK421116)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-HRSV Post-Fusion Glycoprotein Reference Antibody (ADI-14359, RUO) (VK421116)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价