



| 货号 | HC336106 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 同种型 | IgG |
| 克隆号 | AGEN 2373 |
| 表达系统 | Mammalian cells |
| 靶标 | Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q07011 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | AGEN2373, AGEN-2373, AGEN2373 |
| 背景 | Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
| 文献 | 1. Claire Galand, et al., AGEN2373 is a conditionally-active agonist antibody targeting the co-stimulatory receptor CD137 for the treatment of human malignancies. Journal of Clinical Oncology, 2019. [HC336106] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107) |

SDS-PAGE for Research Grade Anti-Human CD137/TNFRSF9/4-1BB (AGEN 2373)

Detects recombinant human CD137/TNFRSF9 (Catalog No: HC336011) in indirect ELISA





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