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Anti-Human M-CSF Reference Antibody (PD-0360324, RUO) (HY515036)

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规格:
  • 100ug
  • 1mg
  • 5mg
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  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HY515036
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG
克隆号PD-0360324
生物活性CSF1 serves as a fluorescent sensor for the specific recognition of Cu + in aqueous buffer systems, with a K d value of 0.49 pM, and its fluorescence response increases 17-fold upon binding to Cu + [1].
表达系统Mammalian cells
靶标CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P09603
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名PD-0360324, PD0360324, PD0360324
背景

Macrophage colony-stimulating factor 1 (CSF1/M-CSF) is a ~60 kDa protein. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.

文献1. Jia S, et al. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2018;13(7):1844-1852. [HY515036]
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CSF1/M-CSF (PD-0360324)

  • Bioactivity

    Detects recombinant human CSF1/M-CSF (Catalog No: HY515011) in indirect ELISA

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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