



| 货号 | HY515016 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Research Grade Lacnotuzumab (HY515016) is a humanized monoclonal antibody detecting CSF1 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian cells |
| 种属 | Human |
| 靶标 | CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P09603 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | MCS-110, 1831128-32-5 |
| 背景 | Macrophage colony-stimulating factor 1 (CSF1,Macrophage colony-stimulating factor 1,CSF-1,Lanimostim,M-CSF,MCSF) is a ~60 kDa protein. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

Detects Human CSF1/M-CSF in indirect ELISAs.

SDS-PAGE for Research Grade Lacnotuzumab.





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