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Anti-Human Podocalyxin Like Reference Antibody (MAI1738, RUO) (HT033016)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HT033016
品牌abinScience
描述
Anti-Human PODXL (MAI1738) (HT033016) is a research-grade recombinant antibody targeting PCLP1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG1-kappa
克隆号MAI1738
表达系统Mammalian cells
靶标PCLP1, Podocalyxin-like protein 1, GCTM-2 antigen, Gp200, PODXL, Podocalyxin, PC, PCLP, PCLP-1
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O00592
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名MAI1738
背景

Podocalyxin (PODXL) is a ~58 kDa protein. Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis.

NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human PODXL (MAI1738).

  • Western blot

    Western blot analysis was performed using anti-PODXL monoclonal antibody at 1µg/ml on various samples.
    Lane 1: recombinant human PODXL (Catalog No: HT033012)
    Lane 2: negative control

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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