Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO) (HV456016)

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概述
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概述

货号	HV456016
品牌	abinScience
描述	remzistotug (HV456016) is a research-grade recombinant antibody targeting CD112. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG1, Kappa
种属	Human
克隆类型	Monoclonal
靶标	CD112/Nectin-2/PVRL2
内毒素水平	< 10 EU/mg
纯度	>95% as determined by SDS-PAGE.
Accession号	Q92692
状态	Liquid
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	2920425-39-2
背景	Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. 1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705 2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade remzistotug

参考文献

产品说明书

Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO) (HV456016)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO) (HV456016)

概述

图片

参考文献

产品说明书

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