Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Retlirafusp Alfa, RUO) (HV974406)

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规格：

100ug
1mg
5mg
10mg
25mg
50mg
100mg

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概述
图片
参考文献
产品说明书

HV974406

abinScience

种属反应性

Human

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Human

IgG4-kappa

SHR-1701 (10 ug/mL) can inhibit TGF-β signaling pathway, activate PI3K/Akt/Erk signaling pathway, rescue lymphocytes and restore the anti-tumor function of peripheral blood CD8 + T cells in patients with lung cancer [1].

Mammalian cells

Monoclonal

经测试应用

B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, TGFR-2, TbetaR-II, TGF-beta type II receptor, TGFBR2, TGF-beta receptor type-2, TGF-beta receptor type II, Transforming growth factor-beta receptor type II

内毒素水平

< 10 EU/mg

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9NZQ7 & P37173

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

SHR-1701

1. Bo Cheng, et al. Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer. Cancer Commun (Lond). 2022 Jan;42(1):17-36. [HV974406]

For research use only. Not suitable for clinical or therapeutic use.

SDS-PAGE

SDS-PAGE for Research Grade Retlirafusp Alfa.
Bioactivity

Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human PDL1 (Catalog No: HV974011)
Lane 2: Negative control

产品说明书

Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Retlirafusp Alfa, RUO).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Retlirafusp Alfa, RUO) (HV974406)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Retlirafusp Alfa, RUO) (HV974406)

概述

图片

参考文献

产品说明书

相关产品推荐

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