Anti-Human BCMA/TNFRSF17 & CD3 epsilon Reference Antibody (Vonsetamig, RUO) (HX959196)

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100ug
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概述
图片
参考文献
产品说明书

概述

货号

HX959196

品牌

abinScience

描述

Vonsetamig (HX959196) is a research-grade recombinant antibody targeting CD269. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Human

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

同种型

IgG4-kappa

表达系统

Mammalian cells

经测试应用

WB, FCM

靶标

Tumor necrosis factor receptor superfamily member 17, TNFRSF17, CD269, B-cell maturation protein, BCMA, BCM, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

Q02223 & P07766

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

2408319-33-3

背景

Teclistamab is an active T cell–redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

图片

SDS-PAGE

SDS-PAGE for Research Grade Vonsetamig.
Flow cytometry

Flow-cytometry using anti-human CD3E antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD3E monoclonal antibody (Catalog HX959196, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using anti-human CD269 antibody. Transfected cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD269 monoclonal antibody (Catalog HX959196, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Bioactivity

Detects recombinant CD269 (Catalog No: HX959012) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD3E (Catalog No: HY057021)
Lane 2: Negative control

参考文献

产品说明书

Anti-Human BCMA/TNFRSF17 & CD3 epsilon Reference Antibody (Vonsetamig, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BCMA/TNFRSF17 & CD3 epsilon Reference Antibody (Vonsetamig, RUO) (HX959196)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BCMA/TNFRSF17 & CD3 epsilon Reference Antibody (Vonsetamig, RUO) (HX959196)

概述

图片

参考文献

产品说明书

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