Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 Bispecific Reference Antibody (Xirestomig, RUO) (HC336176)

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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概述
图片
参考文献
产品说明书

概述

货号

HC336176

品牌

abinScience

描述

Xirestomig (HC336176) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Human

应用

ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB

宿主

Human

克隆类型

Monoclonal

同种型

IgG1-scFv_L2 dimer

经测试应用

靶标

4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9, B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

Q07011 & Q9NZQ7

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

Bispecific, 2756879-35-1

背景

Enristomig is an anti-TNFRSF9/CD274 monoclonal antibody.

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

SDS-PAGE

SDS-PAGE for Research Grade Xirestomig.
Bioactivity

Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.
Bioactivity

Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human PDL1 (Catalog No: HV974011)
Immunofluorescence

Immunofluorescence staining of HDLM2 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.
Immunofluorescence

Immunofluorescence staining of HEK293T cells overexpressing PD-L1 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.

参考文献

产品说明书

Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 Bispecific Reference Antibody (Xirestomig, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 Bispecific Reference Antibody (Xirestomig, RUO) (HC336176)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 Bispecific Reference Antibody (Xirestomig, RUO) (HC336176)

概述

图片

参考文献

产品说明书

相关产品推荐

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