Anti-Human MMP-14/MT1-MMP Reference Antibody (RLVT 14-02, RUO) (HW299036)

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概述

货号	HW299036
品牌	abinScience
描述	Anti-Human MMP14 Antibody (RLVT 14-02) (HW299036) is a research-grade recombinant antibody targeting MT-MMP 1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型	IgG
克隆号	RLVT 14-02
表达系统	Mammalian cells
靶标	MT-MMP 1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14, MTMMP1, MT1-MMP, MMP-14, MMP-X1, MT1MMP
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P50281
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	RLVT14-02, RLVT-14-02, RLVT14-02
背景	Matrix metalloproteinase-14 (MMP14) is a ~65 kDa protein. Endopeptidase that degrades various components of the extracellular matrix such as collagen. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. Activates progelatinase A/MMP2, thereby acting as a positive regulator of cell growth and migration. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. May be involved in actin cytoskeleton reorganization by cleaving PTK7. 1. Sato, H. et al. (1994) Nature 370, 61-5. PMID: 8015608 2. Gu, G. et al. (2012) Journal of cellular biochemistry 113, 1013-21. PMID: 22065321 3. Noda, K. et al. (2003) Investigative ophthalmology & visual science 44, 2163-70. PMID: 12714657 4. Golubkov, VS. et al. (2010) The Journal of biological chemistry 285, 35740-9. PMID: 20837484 5. Jin, G. et al. (2011) The EMBO journal 30, 2281-93. PMID: 21572390 6. Cork, SM. et al. (2012) Oncogene 31, 5144-52. PMID: 22330140 7. Chow, CFW. et al. (2022) Nature metabolism 4, 203-212. PMID: 35177851
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human MMP14 Antibody (RLVT 14-02)

参考文献

产品说明书

Anti-Human MMP-14/MT1-MMP Reference Antibody (RLVT 14-02, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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质量

浓度

体积

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g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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Anti-Human MMP-14/MT1-MMP Reference Antibody (RLVT 14-02, RUO) (HW299036)

概述

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产品说明书

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实验相关试剂

Anti-Human MMP-14/MT1-MMP Reference Antibody (RLVT 14-02, RUO) (HW299036)

概述

图片

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产品说明书

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