

| 货号 | VK421266 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human respiratory syncytial virus A (HRSV-A) |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG1 |
| 克隆号 | RSM01 |
| 生物活性 | RSM-01 tightly binds to the highly conserved Ø site on the Pre-F protein, blocks viral conformational changes, inhibits viral fusion with host cell membranes, and prevents viral entry into cells. It exhibits ultra-high neutralizing activity against both RSV subtype A and subtype B [1]. |
| 表达系统 | Mammalian cells |
| 靶标 | F, Fusion glycoprotein F0, Prefusion, Pre-F |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P03420 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | RSM-01, RSM01, RSM01 |
| 背景 | Fusion glycoprotein F0 (Prefusion/Pre-F) is a ~63 kDa protein. Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins. |
| 文献 | 1. Scotta MC, et al. Current strategies and perspectives for active and passive immunization against Respiratory Syncytial Virus in childhood. J Pediatr (Rio J). 2023;99 Suppl 1(Suppl 1):S4-S11. [VK421266] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-HRSV Prefusion/Pre-F Antibody (RSM01)



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