货号 | HS856036 |
---|---|
品牌 | abinScience |
种属反应性 | Human |
应用 | Research Grade Biosimilar |
宿主 | Humanized |
同种型 | IgG1-kappa |
表达系统 | Mammalian Cells |
种属 | Human |
克隆类型 | Monoclonal |
靶标 | CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A, IL17F, Interleukin-17F, IL-17F, Cytokine ML-1 |
内毒素水平 | Please contact with the lab for this information. |
纯度 | >95% as determined by SDS-PAGE. |
纯化方式 | Protein A/G purified from cell culture supernatant. |
Accession号 | Q16552 & Q96PD4 |
状态 | Liquid |
保存溶液 | 0.01M PBS, pH 7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
别名 | CDP4940, UCB-4940, UCB4940, CAS: 1418205-77-2 |
背景 | Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises IL-17A and IL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation. |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Detects IL17F in indirect ELISAs.
SEC-HPLC detection for Research Grade Bimekizumab.
Detects Human IL17A in indirect ELISAs.
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