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Anti-Human Tau Reference Antibody (Moponetug, RUO) (HY086146)

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  • 1mg
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概述
货号HY086146
品牌abinScience
描述
moponetug (HY086146) is a research-grade recombinant antibody targeting MAPT/Tau/PHF-tau.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
种属反应性Human
应用ELISA, FACS, Functional assay
宿主Human
同种型IgG1, kappa
靶标MAPT/Tau/PHF-tau
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE
Accession号P10636
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名CAS: 3031519-40-8
背景

Microtubule-associated protein tau is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311
2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Research Grade moponetug

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human Tau Reference Antibody (Moponetug, RUO)

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