Anti-Human CD4 Reference Antibody (Tregalizumab, RUO) (HF998036)

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概述

货号	HF998036
品牌	abinScience
描述	Research Grade Tregalizumab (HF998036) is a humanized monoclonal antibody detecting T-cell surface antigen T4/Leu-3 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型	IgG1-kappa
表达系统	Mammalian cells
种属	Human
经测试应用	WB
靶标	T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, CD4
内毒素水平	< 10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P01730
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	BT-061, hB-F5, hBF5(H37L_L4M), 1207446-68-1
背景	T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4,CD4) is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 (E356D/M358L), kappa Recombinant Isotype Control Antibody (HyHEL-10) (HV080013)

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Bioactivity

Detects Human CD4 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Tregalizumab.
Western blot

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998011)
Lane 2: negative control

参考文献

产品说明书

Anti-Human CD4 Reference Antibody (Tregalizumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD4 Reference Antibody (Tregalizumab, RUO) (HF998036)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD4 Reference Antibody (Tregalizumab, RUO) (HF998036)

概述

图片

参考文献

产品说明书

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