

| 货号 | HF998046 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Research Grade Cedelizumab (HF998046) is a humanized monoclonal antibody detecting T-cell surface antigen T4/Leu-3 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG4-kappa |
| 表达系统 | Mammalian cells |
| 种属 | Human |
| 克隆类型 | Monoclonal |
| 靶标 | T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, CD4 |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P01730 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | ORTHOCLONE OKT4 A, 156586-90-2 |
| 背景 | T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4,CD4) is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Cedelizumab.



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