

| 货号 | HV612116 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Research Grade elfetabart (HV612116) is a human monoclonal antibody. Suitable for Human.
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| 种属反应性 | Human | ||||
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| 宿主 | Human | ||||
| 同种型 | IgG1, kappa | ||||
| 克隆类型 | Monoclonal | ||||
| 内毒素水平 | < 10 EU/mg | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q5ZPR3 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | CD276 antigen (B7-H3) is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. CD276 is the therapeutic target of omburtamab (clinical). | ||||
| Note | For research use only. |

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