

| 货号 | PX-P5786 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human IL25/IL17E Protein, N-His (PX-P5786) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q9H293 |
| 蛋白长度 | Met28-Gly177 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 19.44 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Interleukin-25, IL-25, IL17E, IL25, IL-17E, Interleukin-17E |
| 背景 | Interleukin-25 (IL25/IL17E) is a ~20 kDa protein. Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production. Promotes and augments T-helper type 2 responses locally or systemically. Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction. In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13. Also induces the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways. 1. Wong, CK. et al. (2005) American journal of respiratory cell and molecular biology 33, 186-94. PMID: 15860795 2. Wu, L. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 4528-34. PMID: 25821217 3. Fort, MM. et al. (2001) Immunity 15, 985-95. PMID: 11754819 |
| Note | For research use only. |

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