Recombinant Human BCL2 Protein, C-His (PX-P4715)

概述
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参考文献

概述

货号	PX-P4715
品牌	ProteoGenix
描述	Recombinant Human BCL2 Protein, C-His (PX-P4715) expressed in E. coli, Purity: >90% as determined by SDS-PAGE.. Highlights High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy. E. coli Expression — Optimized for functional studies.
表达系统	E. coli
Accession号	P10415
蛋白长度	Met1-Asp211
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	25.62 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Apoptosis regulator Bcl-2, BCL2
背景	Apoptosis regulator Bcl-2 (BCL2) is a ~26 kDa protein. Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function. 1. Eguchi, Y. et al. (1992) Nucleic acids research 20, 4187-92. PMID: 1508712 2. Yin, XM. et al. (1994) Nature 369, 321-3. PMID: 8183370 3. Ruvolo, PP. et al. (2001) Leukemia 15, 515-22. PMID: 11368354 4. Wei, Y. et al. (2008) Molecular cell 30, 678-88. PMID: 18570871 5. Chen, D. et al. (2010) The Journal of biological chemistry 285, 38214-23. PMID: 20889974 6. Strappazzon, F. et al. (2011) The EMBO journal 30, 1195-208. PMID: 21358617 7. Bruey, JM. et al. (2007) Cell 129, 45-56. PMID: 17418785
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human BCL2 Protein, C-His (PX-P4715)

概述

图片

参考文献

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重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human BCL2 Protein, C-His (PX-P4715)

概述

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参考文献

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