Recombinant Human CDK4 Protein, N-His (PX-P5637)

概述
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参考文献

概述

货号	PX-P5637
品牌	ProteoGenix
描述	Recombinant Human CDK4 Protein, N-His (PX-P5637) expressed in E. coli, Purity: >90% as determined by SDS-PAGE.. Highlights High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy. E. coli Expression — Optimized for functional studies.
表达系统	E. coli
Accession号	P11802
蛋白长度	Met1-Glu303
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	36.04 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Cell division protein kinase 4, PSK-J3, Cyclin-dependent kinase 4, CDK4
背景	Cyclin-dependent kinase 4 (CDK4) is a ~33 kDa protein. Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity.
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human CDK4 Protein, N-His (PX-P5637)

概述

图片

参考文献

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重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human CDK4 Protein, N-His (PX-P5637)

概述

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参考文献

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