Recombinant Human DES/Desmin Protein, N-His (PX-P4711)

概述
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参考文献

概述

货号	PX-P4711
品牌	ProteoGenix
描述	Recombinant Human DES/Desmin Protein, N-His (PX-P4711) expressed in E. coli, Purity: >90% as determined by SDS-PAGE.. Highlights High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy. E. coli Expression — Optimized for functional studies.
表达系统	E. coli
Accession号	P17661
蛋白长度	Met1-Leu470
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	55.85 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Desmin, DES
背景	Desmin is a ~53 kDa protein. Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction. Required for nuclear membrane integrity, via anchoring at the cell tip and nuclear envelope, resulting in maintenance of microtubule-derived intracellular mechanical forces. 1. Hnia, K. et al. (2015) Cell and tissue research 360, 591-608. PMID: 25358400 2. Brodehl, A. et al. (2013) Circulation. Cardiovascular genetics 6, 615-23. PMID: 24200904 3. Clemen, CS. et al. (2015) Acta neuropathologica 129, 297-315. PMID: 25394388 4. Brodehl, A. et al. (2016) Journal of molecular and cellular cardiology 91, 207-14. PMID: 26724190
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human DES/Desmin Protein, N-His (PX-P4711)

概述

图片

参考文献

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重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human DES/Desmin Protein, N-His (PX-P4711)

概述

图片

参考文献

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