

| 货号 | PX-P4790 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human PCK2 Protein, N-His (PX-P4790) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q16822 |
| 蛋白长度 | Ala292-Met640 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 41.33 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | PEPCK-M, PEPCK2, Phosphoenolpyruvate carboxykinase [GTP], mitochondrial, PCK2 |
| 背景 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) is a ~70 kDa protein. Mitochondrial phosphoenolpyruvate carboxykinase that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Can play an active role in glyceroneogenesis and gluconeogenesis. Also acts as a serine/threonine-protein kinase: phosphorylates and activates ACSL4, thereby promoting ferroptosis. 1. Escós, M. et al. (2016) Biochemistry and biophysics reports 7, 124-129. PMID: 28955899 2. Li, Z. et al. (2024) Nature chemical biology 20, 1341-1352. PMID: 38720107 |
| Note | For research use only. |

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