

| 货号 | HB714021 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human CD123/IL3RA Protein, C-Fc (HB714021) expressed in Mammalian Cells, spanning Met1-Arg305. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | P26951 |
| 蛋白长度 | Met1-Arg305 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 61.53 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | CD123, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, IL3R, IL3RA, Interleukin-3 receptor subunit alpha |
| 背景 | Interleukin-3 receptor subunit alpha is a ~43 kDa protein. Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program. 1. Huang, S. et al. (1999) Stem cells (Dayton, Ohio) 17, 265-72. PMID: 10527461 |
| Note | For research use only |

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