

| 货号 | MB984021 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Mouse CD9 Protein, N-Fc (MB984021) expressed in Mammalian Cells, spanning Thr110-Ile193. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | P40240 |
| 蛋白长度 | Thr110-Ile193 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Mus musculus (Mouse) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 37.60 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | 5H9 antigen, CD9, CD9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, MIC3, MRP-1, Motility-related protein, TSPAN29, Tetraspanin-29, Tspan-29, p24 |
| 背景 | CD9 antigen is a ~25 kDa protein. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption. 1. Le Naour, F. et al. (2000) Science (New York, N.Y.) 287, 319-21. PMID: 10634790 2. Miyado, K. et al. (2000) Science (New York, N.Y.) 287, 321-4. PMID: 10634791 3. Kaji, K. et al. (2000) Nature genetics 24, 279-82. PMID: 10700183 4. Ishibashi, T. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 96-102. PMID: 14715942 5. Jégou, A. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 10946-51. PMID: 21690351 6. Charrin, S. et al. (2013) Nature communications 4, 1674. PMID: 23575678 7. Takeda, Y. et al. (2003) The Journal of cell biology 161, 945-56. PMID: 12796480 9. Takeda, Y. et al. (2008) The Journal of biological chemistry 283, 26089-97. PMID: 18662991 |
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理