

| 货号 | HC684032 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human HTR4 Protein, N-GST & C-His (HC684032) expressed in E. coli, spanning Arg214-Thr260. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q13639 |
| 蛋白长度 | Arg214-Thr260 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Remove endotoxin and sterilization is required for cell assay. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 33.51 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | 5-HT-4, 5-HT4, 5-hydroxytryptamine receptor 4, HTR4, Serotonin receptor 4 |
| 背景 | 5-hydroxytryptamine receptor 4 is a ~43 kDa protein. G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. 1. Mialet, J. et al. (2000) British journal of pharmacology 130, 527-38. PMID: 10821780 2. Kamel, R. et al. (2005) Biochemical pharmacology 70, 1009-18. PMID: 16102731 3. Huang, S. et al. (2022) Molecular cell 82, 2681-2695.e6. PMID: 35714614 4. Blondel, O. et al. (1998) Journal of neurochemistry 70, 2252-61. PMID: 9603189 |
| Note | For research use only |

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