

| 货号 | HV696032 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human DGKD Protein, N-His (HV696032) expressed in E. coli, spanning Ser56-Asn314. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q86XP1 |
| 蛋白长度 | Ser56-Asn314 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 31.62 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | DAG kinase eta, DGK-eta, DGKH, Diacylglycerol kinase eta, Diglyceride kinase eta, EC:2.7.1.107 |
| 背景 | Diacylglycerol kinase eta is a ~134 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization. 1. Murakami, T. et al. (2003) The Journal of biological chemistry 278, 34364-72. PMID: 12810723 2. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095 3. Yasuda, S. et al. (2009) The Journal of biological chemistry 284, 29559-70. PMID: 19710016 |
| Note | For research use only |

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