

| 货号 | HF703041 |
|---|---|
| 品牌 | abinScience |
| 描述 |
GMP Grade Human Erythropoietin/EPO (Tag Free) (HF703041) expressed in Mammalian cells. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | P01588 |
| 蛋白长度 | Ala28-Arg193 |
| 应用 | ELISA, Functional assay |
| 种属 | Homo sapiens (Human) |
| 生物活性 | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is ≤0.1 ng/mL,corresponding to a specific activity of ≥ 1.5 x 105 IU/mg. |
| 性质 | Recombinant |
| 内毒素水平 | <0.01 EU/ug |
| 纯度 | >95% as determined by SDS-PAGE. |
| 预测分子量 | 18.3 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol, 0.01% Tween 80, pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | EPO, Epoetin, Erythropoietin |
| 背景 | Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. 1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061 2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 |
| Note | For research use only. |

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