

| 货号 | HB058031 |
|---|---|
| 品牌 | abinScience |
| 描述 |
GMP Grade Human Coagulation Factor III/Tissue Factor (Tag Free) (HB058031) expressed in Mammalian cells. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | P13726 |
| 蛋白长度 | Ser33-Glu251 |
| 应用 | ELISA, Functional assay |
| 种属 | Homo sapiens (Human) |
| 生物活性 | Measured by its ability to activate Coagulation Factor VII in cleaving a fluorogenic peptide substrate Boc-VPR-AMC . The AC50 is < 5 μg/ml. |
| 性质 | Recombinant |
| 内毒素水平 | <0.01 EU/ug |
| 纯度 | >95% as determined by SDS-PAGE. |
| 预测分子量 | 24.8 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol, 0.01% Tween 80, pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | It is recommended to redissolve in sterile deionized water |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | CD142, Coagulation factor III, F3, TF, Thromboplastin, Tissue factor |
| 背景 | Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak). |
| Note | For research use only. |

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