InVivoMAb Anti-Human IL-11 Antibody (X203) (HB978010)

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规格：

100ug
1mg

数量：

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概述

货号	HB978010
品牌	abinScience
描述	InVivoMAb Anti-Human IL11 Antibody (X203) [X203] (HB978010) is a mouse monoclonal antibody detecting Interleukin-11 in FuncS. Suitable for Human.
种属反应性	Human
应用	FuncS
同种型	IgG2a, kappa
克隆号	X203
经测试应用	WB
靶标	Interleukin-11, IL-11, Adipogenesis inhibitory factor, AGIF, Oprelvekin, IL11
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P20809
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Interleukin-11 (IL11) is a ~21 kDa protein. Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling'. 1. Paul, SR. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 7512-6. PMID: 2145578 2. Harmegnies, D. et al. (2003) The Biochemical journal 375, 23-32. PMID: 12919066 3. Lamertz, L. et al. (2018) Science signaling 11. PMID: 30279168
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

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SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Human IL11 Antibody (X203)
Bioactivity

Detects recombinant human IL11-SUMO (Catalog No: HB978022) in indirect ELISA
Western blot

Western blot analysis was performed using anti-IL11 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human IL11 (Catalog No: HB978022)
Lane 2: negative control

参考文献

产品说明书

InVivoMAb Anti-Human IL-11 Antibody (X203).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human IL-11 Antibody (X203) (HB978010)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human IL-11 Antibody (X203) (HB978010)

概述

图片

参考文献

产品说明书

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