InVivoMAb Anti-Human Thrombopoietin R/Tpo R Antibody (3D9) (HW601010)

价格:

规格：

100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HW601010

品牌

abinScience

描述

InVivoMAb Anti-Human CD110/TPOR Antibody (3D9) [3D9] (HW601010) is a human monoclonal antibody detecting TPO-R in Agonist, ELISA. Suitable for Human.

种属反应性

Human

应用

Agonist, ELISA

宿主

Human

同种型

IgG1

克隆号

3D9

克隆类型

Monoclonal

靶标

TPO-R, TPOR, Thrombopoietin receptor, MPL, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

相关产品

pH 7.4 Dilution Buffer

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P40238

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Thrombopoietin receptor (CD110/TPOR) is a ~71 kDa protein. Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation. Upon activation by THPO, induces rapid tyrosine phosphorylation and activation of JAK2, providing docking sites for many signaling proteins such as STAT5, SHIP/INPP5D, GRB2, SOS1 and PI3K. In turn, These signaling cascades lead to the proliferation, survival, and differentiation of megakaryocytes, ultimately leading to increased platelet production.

1. Royer, Y. et al. (2005) The Journal of biological chemistry 280, 27251-61. PMID: 15899890

2. Tsutsumi, N. et al. (2023) Cell 186, 4189-4203.e22. PMID: 37633268

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Human CD110/TPOR Antibody (3D9)

参考文献

产品说明书

InVivoMAb Anti-Human Thrombopoietin R/Tpo R Antibody (3D9).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human Thrombopoietin R/Tpo R Antibody (3D9) (HW601010)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human Thrombopoietin R/Tpo R Antibody (3D9) (HW601010)

概述

图片

参考文献

产品说明书

相关产品推荐

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