注册
CN
首页 > 产品中心 > 抗体 > Invivo 体内抗体

InVivoMAb Anti-Mouse IL-11 Antibody (Iv0284) (MB978010)

价格:
规格：
  • 50ug
  • 100ug
  • 1mg
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号MB978010
品牌abinScience
描述
InVivoMAb Anti-Mouse IL11 Antibody (Iv0284) [Iv0284] (MB978010) is a mouse monoclonal antibody detecting Interleukin-11 in ELISA, FCM, Neutralization, WB, in vivo research. Suitable for Mouse.
Highlights
  • ●Multi-Application — Validated across multiple applications.
  • ●Flow Cytometry — Validated for flow cytometry applications.
种属反应性Mouse
应用ELISA, FCM, Neutralization, WB, in vivo research
同种型IgG2a, kappa
克隆号Iv0284
靶标Interleukin-11, IL-11, Il11
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P47873
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interleukin-11 (IL11) is a ~21 kDa protein. Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling'.

1. Morris, JC. et al. (1996) Experimental hematology 24, 1369-76. PMID: 8913282
2. Nishina, T. et al. (2012) Science signaling 5, ra5. PMID: 22253262
3. Barton, VA. et al. (1999) The Journal of biological chemistry 274, 5755-61. PMID: 10026196
4. Putoczki, TL. et al. (2013) Cancer cell 24, 257-71. PMID: 23948300
NoteFor research use only.
Isotype ControlMouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
图片

  • SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Mouse IL11 Antibody (Iv0284)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

InVivoMAb Anti-Mouse IL-11 Antibody (Iv0284)

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2