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InVivoMAb Anti-Human F12 Antibody (Iv0164) (ARO-A13199)

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概述
货号ARO-A13199
品牌ProteoGenix
描述
InVivoMAb Anti-Human F12 Antibody (Iv0164) [Iv0164] (ARO-A13199) is a human monoclonal antibody detecting F12, HAF, Hageman factor, Beta-factor XIIa part 2, Coagulation factor XII in ELISA, Neutralization, WB. Suitable for Human.
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, Neutralization, WB
宿主Human
同种型IgG4, lambda
克隆号Iv0164
克隆类型Monoclonal
靶标F12, HAF, Hageman factor, Beta-factor XIIa part 2, Coagulation factor XII
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P00748
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Coagulation factor XII (F12/Coagulationfactor XII) is a ~67 kDa protein. Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

1. Naito, K. et al. (1991) The Journal of biological chemistry 266, 7353-8. PMID: 2019570
2. MacQuarrie, JL. et al. (2011) Blood 117, 4134-41. PMID: 21304106
3. Brunnée, T. et al. (1993) Blood 81, 580-6. PMID: 8427954
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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