InVivoMAb Anti-Human/Mouse ANGPTL4 Antibody (Iv0129) (ARO-A13247)

概述
图片
参考文献

概述

货号	ARO-A13247
品牌	ProteoGenix
描述	InVivoMAb Anti-Human/Mouse ANGPTL4 Antibody (Iv0129) [Iv0129] (ARO-A13247) is a mouse monoclonal antibody detecting PGAR, Angiopoietin-related protein 4, Hepatic fibrinogen/angiopoietin-related protein, ANGPTL4, Angiopoietin-like protein 4, HFARP, ARP4 in Neutralization. Suitable for Human, Mouse. Highlights Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background. Validated for Neutralization — Optimized for consistent performance. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse
应用	Neutralization
宿主	Mouse
同种型	IgG2a, kappa
克隆号	Iv0129
克隆类型	Monoclonal
靶标	PGAR, Angiopoietin-related protein 4, Hepatic fibrinogen/angiopoietin-related protein, ANGPTL4, Angiopoietin-like protein 4, HFARP, ARP4
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q9BY76
状态	Liquid
保存溶液	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Angiopoietin-related protein 4 (ANGPTL4) is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis. 1. Yin, W. et al. (2009) The Journal of biological chemistry 284, 13213-22. PMID: 19270337 2. Lei, X. et al. (2011) The Journal of biological chemistry 286, 15747-56. PMID: 21398697 3. Mysling, S. et al. (2016) eLife 5. PMID: 27929370 4. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144 5. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458 6. Cazes, A. et al. (2006) Circulation research 99, 1207-15. PMID: 17068295
Note	For research use only. Not suitable for clinical or therapeutic use.

图片

参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human/Mouse ANGPTL4 Antibody (Iv0129) (ARO-A13247)

概述

图片

参考文献

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human/Mouse ANGPTL4 Antibody (Iv0129) (ARO-A13247)

概述

图片

参考文献

相关产品推荐

获取报价