InVivoMAb Anti-Human IFNG/IFN-gamma (Iv0049) (ARO-A13325)

概述
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参考文献

概述

货号	ARO-A13325
品牌	ProteoGenix
描述	InVivoMAb Anti-Human IFNG/IFN-gamma (Iv0049) [Iv0049] (ARO-A13325) is a human monoclonal antibody detecting Interferon gamma, IFN-gamma, Immune interferon, IFNG, IFN-γ in ELISA, Neutralization. Suitable for Human. Highlights Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, Neutralization
宿主	Human
同种型	IgG1
克隆号	Iv0049
克隆类型	Monoclonal
靶标	Interferon gamma, IFN-gamma, Immune interferon, IFNG, IFN-γ
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P01579
状态	Liquid
保存溶液	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Interferon gamma (IFNG/IFN-gamma) is a ~19 kDa protein. Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. 1. El Bougrini, J. et al. (2006) Cellular and molecular biology (Noisy-le-Grand, France) 52, 9-15. PMID: 16914093 2. Hisamatsu, H. et al. (1996) The Journal of experimental medicine 183, 1807-16. PMID: 8666937 3. Greenlund, AC. et al. (1993) The Journal of biological chemistry 268, 18103-10. PMID: 8349687 4. Akiyama, K. et al. (1994) FEBS letters 343, 85-8. PMID: 8163024 5. Fabunmi, RP. et al. (2001) Journal of cell science 114, 29-36. PMID: 11112687 6. Lah, TT. et al. (1995) FEBS letters 363, 85-9. PMID: 7729559
Note	For research use only. Not suitable for clinical or therapeutic use.

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公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human IFNG/IFN-gamma (Iv0049) (ARO-A13325)

概述

图片

参考文献

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重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human IFNG/IFN-gamma (Iv0049) (ARO-A13325)

概述

图片

参考文献

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