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InVivoMAb Anti-Human EPO (Iv0055) (ARO-A13319)

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概述
货号ARO-A13319
品牌ProteoGenix
描述
InVivoMAb Anti-Human EPO (Iv0055) [Iv0055] (ARO-A13319) is a human monoclonal antibody detecting EPO, Erythropoietin, Epoetin in ELISA, FCM, Neutralization. Suitable for Human.
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, FCM, Neutralization
宿主Human
同种型IgG1, kappa
克隆号Iv0055
克隆类型Monoclonal
靶标EPO, Erythropoietin, Epoetin
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P01588
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.

1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061
2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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