

| 货号 | MB199010 |
|---|---|
| 品牌 | abinScience |
| 描述 |
InVivoMAb Anti-Mouse CD40 Ligand/TNFSF5 Antibody (MR-1) (MB199010) is a armenian hamster monoclonal antibody detecting CD40 Ligand/TNFSF5 in ELISA, in vivo study. Suitable for Mouse.
Highlights
|
| 种属反应性 | Mouse |
| 应用 | in vivo blocking of CD40/CD40L signaling, in vitro blocking of CD40/CD40L signaling, WB |
| 宿主 | Armenian Hamster |
| 克隆类型 | Monoclonal |
| 同种型 | IgG, kappa |
| 克隆号 | MR-1 |
| 靶标 | CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD154, CD40 ligand, membrane form, CD40 ligand, soluble form, sCD40L, CD40LG, CD40L, TNFSF5 |
| 内毒素水平 | < 1 EU/mg as determined by LAL method. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P27548 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | CD40 ligand (CD154/CD40L) is a ~29 kDa protein. Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. 1. Graf, D. et al. (1992) European journal of immunology 22, 3191-4. PMID: 1280226 2. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973 3. Blotta, MH. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 156, 3133-40. PMID: 8617933 4. Mikolajczak, SA. et al. (2004) The Journal of experimental medicine 199, 1025-31. PMID: 15067037 |
| Note | For research use only |

SDS-PAGE for InVivoMAb Anti-Mouse CD40 Ligand/TNFSF5 Antibody (MR-1)



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