Anti-Human SLC4A7 Recombinant Antibody (SAA1974) (HA125013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HA125013

abinScience

种属反应性

Human

ELISA

VHH-mFc

SAA1974

Electroneutral Na/HCO(3) cotransporter, Sodium bicarbonate cotransporter 3, NBC3, Sodium bicarbonate cotransporter 2, NBCn1, Solute carrier family 4 member 7, Bicarbonate transporter, SLC4A6, NBC2, SBC2, Sodium bicarbonate cotransporter 2b, NBC2B, BT, SLC4A7

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9Y6M7

Anti-Human SLC4A7 Antibody (SAA1974) (abinScience Cat# HA125013, RRID:AB_3727738)
_x005F_x000D_

Liquid

30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Sodium bicarbonate cotransporter 3 (SLC4A7) is a ~136 kDa protein. Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Mediates the sodium-dependent bicarbonate transport important for pH recovery after acid load as well as for regulation of steady-state pH in the duodenum and vascular smooth muscle cells. Plays a key role in macrophage acidification, mediating bicarbonate import into the cytoplasm which is crucial for net acid extrusion and maintenance of cytoplasmic pH during phagocytosis. Provides cellular bicarbonate for de novo purine and pyrimidine synthesis and is a key mediator of de novo nucleotide synthesis downstream of mTORC1 signaling in proliferating cells.

1. Pushkin, A. et al. (1999) The Journal of biological chemistry 274, 16569-75. PMID: 10347222

2. Park, M. et al. (2002) The Journal of biological chemistry 277, 50503-9. PMID: 12403779

3. Loiselle, FB. et al. (2003) Molecular membrane biology 20, 307-17. PMID: 14578046

4. Loiselle, FB. et al. (2004) American journal of physiology. Cell physiology 286, C1423-33. PMID: 14736710

5. Sedlyarov, V. et al. (2018) Cell host & microbe 23, 766-774.e5. PMID: 29779931

6. Ali, ES. et al. (2022) Molecular cell 82, 3284-3298.e7. PMID: 35772404

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human SLC4A7 Antibody (SAA1974)

产品说明书

Anti-Human SLC4A7 Recombinant Antibody (SAA1974).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC4A7 Recombinant Antibody (SAA1974) (HA125013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC4A7 Recombinant Antibody (SAA1974) (HA125013)

概述

图片

参考文献

产品说明书

相关产品推荐

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