Anti-Human TMPRSS2 Recombinant Antibody (SAA2325) (HT176023)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HT176023

abinScience

种属反应性

Human

ELISA, Inhibition

VHH-Fc

SAA2325

Transmembrane protease serine 2, EC:3.4.21.122, Serine protease 10, Transmembrane protease serine 2 non-catalytic chain, Transmembrane protease serine 2 catalytic chain, TMPRSS2, PRSS10

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O15393

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Transmembrane protease serine 2 (TMPRSS2) is a ~53 kDa protein. Plasma membrane-anchored serine protease that cleaves at arginine residues. Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.

1. Bestle, D. et al. (2020) Life science alliance 3. PMID: 32703818

2. Fraser, BJ. et al. (2022) Nature chemical biology 18, 963-971. PMID: 35676539

3. Wang, H. et al. (2023) Nature communications 14, 7574. PMID: 37990007

4. McCallum, M. et al. (2024) Cell 187, 4231-4245.e13. PMID: 38964328

5. Lucas, JM. et al. (2014) Cancer discovery 4, 1310-25. PMID: 25122198

6. Wilson, S. et al. (2005) The Biochemical journal 388, 967-72. PMID: 15537383

7. Ko, CJ. et al. (2015) Cancer research 75, 2949-60. PMID: 26018085

For research use only

SDS-PAGE

SDS-PAGE for Anti-Human TMPRSS2 Antibody (SAA2325)

产品说明书

Anti-Human TMPRSS2 Recombinant Antibody (SAA2325).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TMPRSS2 Recombinant Antibody (SAA2325) (HT176023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TMPRSS2 Recombinant Antibody (SAA2325) (HT176023)

概述

图片

参考文献

产品说明书

相关产品推荐

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