Anti-Human LGR4 Recombinant Nanobody (SAA2295) (HV980023)

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50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HV980023

品牌

abinScience

描述

Anti-Human LGR4 Nanobody (SAA2295) [SAA2295] (HV980023) is a alpaca monoclonal antibody detecting LGR4 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

同种型

VHH-His

克隆号

SAA2295

克隆类型

Monoclonal

靶标

G-protein coupled receptor 48, GPR48, LGR4, Leucine-rich repeat-containing G-protein coupled receptor 4

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

Q9BXB1

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.

Note

For research use only

图片

SDS-PAGE

SDS-PAGE for Anti-Human LGR4 Nanobody (SAA2295)

参考文献

产品说明书

Anti-Human LGR4 Recombinant Nanobody (SAA2295).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LGR4 Recombinant Nanobody (SAA2295) (HV980023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LGR4 Recombinant Nanobody (SAA2295) (HV980023)

概述

图片

参考文献

产品说明书

相关产品推荐

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