Anti-Human VEGF & Angiopoietin-2 Bispecific Reference Antibody (Vanucizumab, RUO) (HT073026)

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概述

货号	HT073026
品牌	abinScience
描述	Vanucizumab (HT073026) is a research-grade recombinant antibody targeting Vascular endothelial growth factor A. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型	human IgG1 - kappa - lambda with half-IG VL-CH1/VH-CK crossover
表达系统	Mammalian cells
经测试应用	FCM
靶标	Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A, ANG-2, ANGPT2, Angiopoietin-2
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P15692 & O15123
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Bispecific, RG-7221, RG7221, RO5520985, 1448221-05-3
背景	Zifibancimig is an anti-VEGFA/ANGPT2 IgG1κ monoclonal antibody.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10) (HV080407) Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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Bioactivity

Detects Human VEGFA in indirect ELISAs.
SEC-HPLC

SEC-HPLC detection for Research Grade Vanucizumab.
Bioactivity

Detects Human ANGPT2 in indirect ELISAs.
Flow CytoMetry

Flow-cytometry using FITC anti-human VEGFA&ANGPT2 antibody. U87 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human VEGFA&ANGPT2 monoclonal antibody (Catalog: HT073026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献

产品说明书

Anti-Human VEGF & Angiopoietin-2 Bispecific Reference Antibody (Vanucizumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

Anti-Human VEGF & Angiopoietin-2 Bispecific Reference Antibody (Vanucizumab, RUO) (HT073026)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human VEGF & Angiopoietin-2 Bispecific Reference Antibody (Vanucizumab, RUO) (HT073026)

概述

图片

参考文献

产品说明书

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