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Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO) (HB996046)

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概述
货号HB996046
品牌abinScience
描述
Blinatumomab (HB996046) is a research-grade recombinant antibody targeting CD19. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型(scFv-kappa-heavy)-(scFv-heavy-kappa)
表达系统Mammalian cells
靶标CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Purified by Nickel column.
Accession号P15391 & P07766
状态Liquid
保存溶液 30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Bispecific, CD19, AMG103, BITEMT-103, MEDI-538, MT103, bscCD19xCD3, 853426-35-4
背景Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia.
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlBiTE Format Isotype Control for Bispecific Reference Antibody (HP473013)
图片

  • SDS-PAGE

    SDS-PAGE for Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)

  • Bioactivity

    SEC-HPLC detection for Research Grade Blinatumomab.

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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