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Anti-Ganglioside GD3 Reference Antibody (Mitumomab, RUO) (YP464026)

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概述
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参考文献
产品说明书

概述

货号	YP464026
品牌	abinScience
描述	Mitumomab (YP464026) is a research-grade recombinant antibody targeting Ganglioside GD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	General
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Mouse
同种型	IgG2b-kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Ganglioside GD3
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	BEC2, CAS: 216503-58-1
背景	Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma. • GD3 ganglioside and apoptosis., PMID:12531552 • Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474 • Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197 • A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669 • Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994 • Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773 • Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804 • Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478 • Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859 • Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428
Note	For research use only. Not suitable for clinical or therapeutic use.

图片

SDS-PAGE

SDS-PAGE for Research Grade Mitumomab

参考文献

产品说明书

Anti-Ganglioside GD3 Reference Antibody (Mitumomab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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公式

C₁ × V₁ = C₂ × V₂

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母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Ganglioside GD3 Reference Antibody (Mitumomab, RUO)

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