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InVivo Plus Anti-Mouse CTLA-4 Antibody(9D9) (MB651209)

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概述
货号MB651209
品牌abinScience
描述
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
  • Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion
同种型IgG2b, kappa
克隆号9D9
靶标CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4
内毒素水平<1 EU/mg
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P09793
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

NoteFor research use only.
Isotype ControlMouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207)
图片
  • SDS-PAGE

    SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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