

| 货号 | MB651209 |
|---|---|
| 品牌 | abinScience |
| 描述 |
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
|
| 种属反应性 | Mouse |
| 应用 | in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion |
| 同种型 | IgG2b, kappa |
| 克隆号 | 9D9 |
| 靶标 | CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4 |
| 内毒素水平 | <1 EU/mg |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P09793 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy). |
| Note | For research use only. |
| Isotype Control | Mouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207) |

SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)



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