Anti-CD94/KLRD1 Polyclonal Antibody (HC299014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HC299014

品牌

abinScience

描述

Anti-CD94/KLRD1 Polyclonal Antibody (HC299014) is a rabbit polyclonal antibody detecting KLRD1 in ELISA, IHC, WB. Suitable for Human, Macaca mulatta, Pan troglodytes, and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD94/KLRD1 (Lys32-Ile179).

靶标

Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94, CD94, KP43, KLRD1

纯化方式

Purified by antigen affinity column.

Accession号

Q13241

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Natural killer cells antigen CD94 (KLRD1) is a ~20 kDa protein. Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal.

1. Boyington, JC. et al. (1999) Immunity 10, 75-82. PMID: 10023772

2. Bhagat, G. et al. (2008) The Journal of clinical investigation 118, 281-93. PMID: 18064301

3. Sullivan, LC. et al. (2007) Immunity 27, 900-11. PMID: 18083576

4. Lin, Z. et al. (2023) Nature immunology 24, 1087-1097. PMID: 37264229

5. Braud, VM. et al. (1998) Nature 391, 795-9. PMID: 9486650

6. Llano, M. et al. (1998) European journal of immunology 28, 2854-63. PMID: 9754572

7. Jabri, B. et al. (2002) Immunity 17, 487-99. PMID: 12387742

8. Valiante, NM. et al. (1997) Immunity 7, 739-51. PMID: 9430220

Note

For research use only.

图片

参考文献

产品说明书

Anti-CD94/KLRD1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD94/KLRD1 Polyclonal Antibody (HC299014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD94/KLRD1 Polyclonal Antibody (HC299014)

概述

图片

参考文献

产品说明书

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