

| 货号 | PX-P5635 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human CD94/KLRD1 Protein, N-His (PX-P5635) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q13241 |
| 蛋白长度 | Lys32-Ile179 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 19.47 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94, CD94, KP43, KLRD1 |
| 背景 | Natural killer cells antigen CD94 (KLRD1) is a ~20 kDa protein. Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal. 1. Boyington, JC. et al. (1999) Immunity 10, 75-82. PMID: 10023772 2. Bhagat, G. et al. (2008) The Journal of clinical investigation 118, 281-93. PMID: 18064301 3. Sullivan, LC. et al. (2007) Immunity 27, 900-11. PMID: 18083576 4. Lin, Z. et al. (2023) Nature immunology 24, 1087-1097. PMID: 37264229 5. Braud, VM. et al. (1998) Nature 391, 795-9. PMID: 9486650 6. Llano, M. et al. (1998) European journal of immunology 28, 2854-63. PMID: 9754572 7. Jabri, B. et al. (2002) Immunity 17, 487-99. PMID: 12387742 8. Valiante, NM. et al. (1997) Immunity 7, 739-51. PMID: 9430220 |
| Note | For research use only. |

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