

| 货号 | HT134014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-OGA Polyclonal Antibody (HT134014) is a rabbit polyclonal antibody detecting OGA in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human OGA (Ser6-Lys240). | ||||||||
| 靶标 | OGA, Protein O-GlcNAcase, Meningioma-expressed antigen 5, Beta-N-acetylhexosaminidase, HEXC, N-acetyl-beta-glucosaminidase, KIAA0679, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, MEA5, MGEA5, Beta-hexosaminidase, NCOAT, Beta-N-acetylglucosaminidase, N-acetyl-beta-D-glucosaminidase | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O60502 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein O-GlcNAcase (OGA) is a ~102 kDa protein. Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Deglycosylates a large and diverse number of proteins, such as CRYAB, ELK1, GSDMD, LMNB1 and TAB1. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity. 1. Gao, Y. et al. (2001) The Journal of biological chemistry 276, 9838-45. PMID: 11148210 2. Wells, L. et al. (2002) The Journal of biological chemistry 277, 1755-61. PMID: 11788610 3. Li, J. et al. (2010) Biochemistry. Biokhimiia 75, 938-43. PMID: 20673219 4. Schimpl, M. et al. (2012) Chemistry & biology 19, 173-8. PMID: 22365600 5. Rao, FV. et al. (2013) Open biology 3, 130021. PMID: 24088714 6. Li, B. et al. (2017) Nature communications 8, 666. PMID: 28939839 7. Yu, F. et al. (2024) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 73, 5-17. PMID: 37962578 | ||||||||
| Note | For research use only. |

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