Anti-Human DNMT1 Polyclonal Antibody (HB924014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HB924014

品牌

abinScience

描述

Anti-Human DNMT1 Polyclonal Antibody (HB924014) is a rabbit polyclonal antibody detecting DNMT1 in ELISA, IHC, WB. Suitable for Bovine and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human DNMT1 (Arg730-Ile907).

靶标

CXXC-type zinc finger protein 9, MCMT, AIM, DNMT1, DNA MTase HsaI, DNMT, DNA (cytosine-5)-methyltransferase 1, Dnmt1, DNA methyltransferase HsaI, M.HsaI, CXXC9

纯化方式

Purified by antigen affinity column.

Accession号

P26358

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

DNA (cytosine-5)-methyltransferase 1 (DNMT1) is a ~183 kDa protein. DNA methyltransferase that methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development.

1. Schlesinger, Y. et al. (2007) Nature genetics 39, 232-6. PMID: 17200670

2. Pradhan, M. et al. (2008) Biochemistry 47, 10000-9. PMID: 18754681

3. Felle, M. et al. (2011) Nucleic acids research 39, 8355-65. PMID: 21745816

4. Zhang, ZM. et al. (2015) Journal of molecular biology 427, 2520-2531. PMID: 26070743

5. Viré, E. et al. (2006) Nature 439, 871-4. PMID: 16357870

8. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human DNMT1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DNMT1 Polyclonal Antibody (HB924014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DNMT1 Polyclonal Antibody (HB924014)

概述

图片

参考文献

产品说明书

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