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Anti-Human DNMT1 Polyclonal Antibody (PTX20099)

概述
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概述

货号	PTX20099
品牌	ProteoGenix
描述	Anti-Human DNMT1 Polyclonal Antibody (PTX20099) is a rabbit polyclonal antibody detecting CXXC-type zinc finger protein 9, MCMT, AIM, DNMT1, DNA MTase HsaI, DNMT, DNA (cytosine-5)-methyltransferase 1, Dnmt1, DNA methyltransferase HsaI, M.HsaI, CXXC9 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
同种型	IgG
克隆类型	Polyclonal
免疫原	E. coli - derived recombinant Human DNMT1 (Arg730-Ile907).
靶标	CXXC-type zinc finger protein 9, MCMT, AIM, DNMT1, DNA MTase HsaI, DNMT, DNA (cytosine-5)-methyltransferase 1, Dnmt1, DNA methyltransferase HsaI, M.HsaI, CXXC9
纯化方式	Purified by antigen affinity column.
Accession号	P26358
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	DNA (cytosine-5)-methyltransferase 1 (DNMT1) is a ~183 kDa protein. DNA methyltransferase that methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. 1. Schlesinger, Y. et al. (2007) Nature genetics 39, 232-6. PMID: 17200670 2. Pradhan, M. et al. (2008) Biochemistry 47, 10000-9. PMID: 18754681 3. Felle, M. et al. (2011) Nucleic acids research 39, 8355-65. PMID: 21745816 4. Zhang, ZM. et al. (2015) Journal of molecular biology 427, 2520-2531. PMID: 26070743 5. Viré, E. et al. (2006) Nature 439, 871-4. PMID: 16357870 8. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human DNMT1 Polyclonal Antibody

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