Anti-Human DNMT1 IP Recombinant Antibody (SAA0251) (HB924013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HB924013

abinScience

种属反应性

Human

ELISA, IF, IP

IgG2a

SAA0251

CXXC-type zinc finger protein 9, MCMT, AIM, DNMT1, DNA MTase HsaI, DNMT, DNA (cytosine-5)-methyltransferase 1, Dnmt1, DNA methyltransferase HsaI, M.HsaI, CXXC9

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P26358

Anti-Human DNMT1 IP Antibody (SAA0251) (abinScience Cat# HB924013, RRID:AB_3729785)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

DNA (cytosine-5)-methyltransferase 1 (DNMT1) is a ~183 kDa protein. DNA methyltransferase that methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development.

1. Schlesinger, Y. et al. (2007) Nature genetics 39, 232-6. PMID: 17200670

2. Pradhan, M. et al. (2008) Biochemistry 47, 10000-9. PMID: 18754681

3. Felle, M. et al. (2011) Nucleic acids research 39, 8355-65. PMID: 21745816

4. Zhang, ZM. et al. (2015) Journal of molecular biology 427, 2520-2531. PMID: 26070743

5. Viré, E. et al. (2006) Nature 439, 871-4. PMID: 16357870

8. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human DNMT1 IP Antibody (SAA0251)

产品说明书

Anti-Human DNMT1 IP Recombinant Antibody (SAA0251).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DNMT1 IP Recombinant Antibody (SAA0251) (HB924013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DNMT1 IP Recombinant Antibody (SAA0251) (HB924013)

概述

图片

参考文献

产品说明书

相关产品推荐

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