Anti-Human NKX2-5 Polyclonal Antibody (HW502014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

HW502014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human NKX2-5 (Ser146-Gly206).

NKX2E, CSX, Homeobox protein Nkx-2.5, NKX2.5, NKX2-5, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E

Purified by antigen affinity column.

Accession号

P52952

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Homeobox protein Nkx-2.5 (NKX2-5) is a ~34 kDa protein. Transcription factor required for the development of the heart and the spleen. During heart development, acts as a transcriptional activator of NPPA/ANF in cooperation with GATA4. May cooperate with TBX2 to negatively modulate expression of NPPA/ANF in the atrioventricular canal. Binds to the core DNA motif of NPPA promoter. Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression.

1. Koss, M. et al. (2012) Developmental cell 22, 913-26. PMID: 22560297

2. Pradhan, L. et al. (2012) Biochemistry 51, 6312-9. PMID: 22849347

3. Pradhan, L. et al. (2016) Biochemistry 55, 1702-10. PMID: 26926761

4. Samokhin, AO. et al. (2018) Science translational medicine 10. PMID: 29899023

For research use only.

产品说明书

Anti-Human NKX2-5 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NKX2-5 Polyclonal Antibody (HW502014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NKX2-5 Polyclonal Antibody (HW502014)

概述

图片

参考文献

产品说明书

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