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Anti-Human NKX2-5 Polyclonal Antibody (ARO-A12305)

概述
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参考文献

概述

货号	ARO-A12305
品牌	ProteoGenix
描述	Anti-Human NKX2-5 Polyclonal Antibody (ARO-A12305) is a rabbit polyclonal antibody detecting NKX2E, CSX, Homeobox protein Nkx-2.5, NKX2.5, NKX2-5, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human NKX2-5 (Ser146-Gly206).
靶标	NKX2E, CSX, Homeobox protein Nkx-2.5, NKX2.5, NKX2-5, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E
纯化方式	Purified by antigen affinity column.
Accession号	P52952
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Homeobox protein Nkx-2.5 (NKX2-5) is a ~34 kDa protein. Transcription factor required for the development of the heart and the spleen. During heart development, acts as a transcriptional activator of NPPA/ANF in cooperation with GATA4. May cooperate with TBX2 to negatively modulate expression of NPPA/ANF in the atrioventricular canal. Binds to the core DNA motif of NPPA promoter. Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression. 1. Koss, M. et al. (2012) Developmental cell 22, 913-26. PMID: 22560297 2. Pradhan, L. et al. (2012) Biochemistry 51, 6312-9. PMID: 22849347 3. Pradhan, L. et al. (2016) Biochemistry 55, 1702-10. PMID: 26926761 4. Samokhin, AO. et al. (2018) Science translational medicine 10. PMID: 29899023
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human NKX2-5 Polyclonal Antibody

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